Prices checked 2026-09-18

The same shot costs $2,388 a year. Or $5,388.

Same class of medication, $3,000 apart. We priced 12 GLP-1 programmes over a full year — every membership fee counted, every teaser rate ignored — and sorted them cheapest first.

How we make money: one company on this page — Coreage Rx — pays us a commission when a reader signs up through our link. It buys them nothing else: not a better score, not a higher place in the table, not the removal of a single criticism. Our scoring method and full disclosure are both public.

Tirzepatide, cheapest first

Every figure below is what you actually pay each month, membership included, multiplied out across a year.

ProgrammePer monthPer yearExtra vs cheapest
Coreage Rx Cheapest
no membership fee
$199$2,388
Zealthy
no membership fee
$216$2,592+$204
Hims & Hers
incl. $39 monthly fee
$238$2,856+$468
Mochi Health
incl. $79 monthly fee
$278$3,336+$948
Eden
incl. $99 monthly fee
$298$3,576+$1,188
TrimRx
no membership fee
$399$4,788+$2,400

See all 10 tirzepatide programmes →

Semaglutide, cheapest first

Cheaper than tirzepatide almost everywhere. Two programmes advertise $99 a month — only one of them charges it.

ProgrammePer monthPer yearExtra vs cheapest
Coreage Rx Cheapest
no membership fee
$149$1,788
Zealthy
no membership fee
$151$1,812+$24
Mochi Health
incl. $79 monthly fee
$178$2,136+$348
Hims & Hers
incl. $39 monthly fee
$188$2,256+$468
Eden
incl. $99 monthly fee
$198$2,376+$588
Henry Meds
no membership fee
$297$3,564+$1,776

See all semaglutide programmes →


Where to start


Before you buy on price alone. Compounded GLP-1s are not FDA-approved and the rules tightened again in 2026. That does not make them unsafe, but it is a real difference from Zepbound and Wegovy. Here is what the current rules actually say.