Prices checked 2026-09-18

The same shot costs $2,388 a year. Or $5,388.

Same class of medication, $3,000 apart. We priced 23 GLP-1 programmes over a full year — every membership fee counted, every teaser rate ignored — and sorted them cheapest first.

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Tirzepatide, cheapest first

Every figure below is what you actually pay each month, membership included, multiplied out across a year.

ProgrammePer monthPer yearExtra vs cheapest
Coreage Rx Cheapest
no membership fee
$199$2,388+$888
SuperHealthy Rx
no membership fee
$135$1,620+$120
Likeness Rx
no membership fee
$199$2,388+$888
Trimi
no membership fee
$125$1,500—
Ozari Health
no membership fee
$125$1,500—
Fifty 410
no membership fee
$133$1,596+$96

See all 20 tirzepatide programmes →

Semaglutide, cheapest first

Cheaper than tirzepatide almost everywhere. Two programmes advertise $99 a month — only one of them charges it.

ProgrammePer monthPer yearExtra vs cheapest
Coreage Rx Cheapest
no membership fee
$139$1,668+$648
SuperHealthy Rx
no membership fee
$85$1,020—
Likeness Rx
no membership fee
$139$1,668+$648
Ozari Health
no membership fee
$86$1,032+$12
Trimi
no membership fee
$99$1,188+$168
Zealthy
no membership fee
$151$1,812+$792

See all semaglutide programmes →


Where to start

Reading the research

Understand how observations, analysis choices and uncertainty shape a trial result.


Before you buy on price alone. Compounded GLP-1s are not FDA-approved and the rules tightened again in 2026. That does not make them unsafe, but it is a real difference from Zepbound and Wegovy. Here is what the current rules actually say.