The same shot costs $2,388 a year. Or $5,388.
Same class of medication, $3,000 apart. We priced 23 GLP-1 programmes over a full year — every membership fee counted, every teaser rate ignored — and sorted them cheapest first.
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Tirzepatide, cheapest first
Every figure below is what you actually pay each month, membership included, multiplied out across a year.
| Programme | Per month | Per year | Extra vs cheapest |
|---|---|---|---|
| Coreage Rx Cheapest no membership fee | $199 | $2,388 | +$888 |
| SuperHealthy Rx no membership fee | $135 | $1,620 | +$120 |
| Likeness Rx no membership fee | $199 | $2,388 | +$888 |
| Trimi no membership fee | $125 | $1,500 | — |
| Ozari Health no membership fee | $125 | $1,500 | — |
| Fifty 410 no membership fee | $133 | $1,596 | +$96 |
See all 20 tirzepatide programmes →
Semaglutide, cheapest first
Cheaper than tirzepatide almost everywhere. Two programmes advertise $99 a month — only one of them charges it.
| Programme | Per month | Per year | Extra vs cheapest |
|---|---|---|---|
| Coreage Rx Cheapest no membership fee | $139 | $1,668 | +$648 |
| SuperHealthy Rx no membership fee | $85 | $1,020 | — |
| Likeness Rx no membership fee | $139 | $1,668 | +$648 |
| Ozari Health no membership fee | $86 | $1,032 | +$12 |
| Trimi no membership fee | $99 | $1,188 | +$168 |
| Zealthy no membership fee | $151 | $1,812 | +$792 |
See all semaglutide programmes →
Where to start
Reading the research
Understand how observations, analysis choices and uncertainty shape a trial result.
Before you buy on price alone. Compounded GLP-1s are not FDA-approved and the rules tightened again in 2026. That does not make them unsafe, but it is a real difference from Zepbound and Wegovy. Here is what the current rules actually say.
