Ranking

Best value GLP-1 programmes

Cheapest is one question; best value is another. Where each programme actually earns what it charges.

Illustration of ascending stacked blocks

Updated 2026-09-18 · every price checked by hand


Cheapest and best value are not the same question. This page is for the second one: where the money you spend actually buys something.

We ran every programme through the scoring rubric, which weighs true monthly cost most heavily but also counts price honesty, clinical support, pharmacy sourcing and how hard it is to cancel. Here is where each one earns its money.

Best overall value: Coreage Rx

Twelve months of tirzepatide on the annual plan total $1,548, equivalent to $129 a month. Twelve separate one-month plans at $199 would total $2,388, an $840 difference. The three- and six-month equivalents are $159 and $139 respectively. Confirm payment and renewal terms before choosing. Full detail in the Coreage Rx tirzepatide review and the semaglutide review.

Best if you have insurance: Mochi Health

That sounds like a contradiction. It is not: Mochi runs an insurance concierge that actually pursues coverage, and a successful claim can cut your cost by an order of magnitude. No other programme in our table treats that as core work. See the Mochi tirzepatide review.

Best no-nonsense middle option: Zealthy

Most of this market advertises a low medication price and recovers the difference in a monthly fee. Zealthy does not, so the $151 you are quoted is the $151 you pay. See the Zealthy semaglutide review.

Best if you will not inject: Henry Meds

The prepaid route is where the value is. Three months of oral semaglutide is $747, or $537 paid in full, which works out near $179 a month — competitive with anything on this page if the format suits you. See the Henry Meds semaglutide review.

Best coaching: Noom

The coaching is the actual product here and it is the best in this comparison. Biomarker monitoring is folded in, and cancellation is straightforward, which is not universal in this market. See the Noom tirzepatide review.

Best for FDA-approved medication: Ro

Ro exited compounded GLP-1s entirely and now works only with FDA-approved products. That is a defensible position and it removes the regulatory question that hangs over every compounded programme on this page. It is also the reason the price is what it is. See the Ro tirzepatide review.

The full price tables

If cost is the only thing you care about, skip all of the above and go straight to the cheapest tirzepatide programmes or the cheapest semaglutide programmes.

ProgrammePer monthPer yearExtra vs cheapest
Coreage Rx Cheapest
no membership fee
$199$2,388+$888
SuperHealthy Rx
no membership fee
$135$1,620+$120
Likeness Rx
no membership fee
$199$2,388+$888
Trimi
no membership fee
$125$1,500—
Ozari Health
no membership fee
$125$1,500—
Fifty 410
no membership fee
$133$1,596+$96
PlexusDx
no membership fee
$189$2,268+$768
Ivím Health
no membership fee
$199$2,388+$888

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Coreage Rx pays us a commission on sign-ups through our links. It does not affect our scores or rankings. How we rate · Disclosure