Guides

Spend less on the same prescription

Practical checks that routinely save four figures a year without changing what is in the syringe.

How to cut your GLP-1 billSeven checks that routinely save $1,000 or more a year on exactly the same prescription.Updated 2026-09-18Annual or monthly?Annual plans carry the best rates and the worst exit terms. How to work out whether the discount is worth it.Updated 2026-10-15Tirzepatide vs semaglutideOne works better. The other is cheaper. Here is the actual size of both gaps.Updated 2026-09-18Is compounded GLP-1 still legal?Yes, but far more narrowly than in 2024 — and the FDA moved again this year. What changed, and what to ask.Updated 2026-09-18How to spot a bad sellerThe FDA sent more than 55 warning letters to online GLP-1 sellers in one day. Here is how to tell a licensed programme from the rest.Updated 2026-09-18The twelve-month costMonth one is the cheapest month you will have. Here is the full-year arithmetic, including the costs nobody puts in the advert.Updated 2026-09-18Medicare, GLP-1s and the $50 monthCMS is running a time-limited programme giving eligible Part D members certain GLP-1s for $50 a month. If you are on Medicare, read this before paying cash for anything.Updated 2026-09-18The approved pills changed the mathsTwo oral GLP-1s were approved either side of the new year, both starting at $149 a month. That undercuts a large part of the compounded market.Updated 2026-09-18What happens when you stopMost people regain a substantial share of the weight. Here is what the research actually found, and what that means for how you plan and budget.Updated 2026-09-18GLP-1s after 50These drugs work at any age. The risks are not identical at every age, and the muscle and bone question deserves more attention than it usually gets.Updated 2026-09-18Titration, properly explainedWhen to step up, when to hold, when to go back down, and why restarting after a gap is the one genuinely dangerous mistake.Updated 2026-09-18How to read your prescriptionWhat the abbreviations mean, and the mg-versus-mL distinction that is the one genuine hazard in this category.Updated 2026-09-18

Reading the research

Understand how observations, analysis choices and uncertainty shape a trial result.