The cheapest tirzepatide programmes

We priced every tirzepatide programme we could get a straight answer out of, added the fees they charge behind the advertised rate, and sorted the list cheapest first. The spread between top and bottom is $3,000 a year.

Coreage Rx is cheapest at $2,388 a year. Henry Meds is dearest at $5,388. Same class of medication in both cases — the difference is almost entirely how each company structures its fees.

Every tirzepatide programme, cheapest first

Prices verified 2026-09-18. "What you actually pay" includes any membership or platform fee charged alongside the medication.

1. Coreage Rx — $2,388 a year

$199 a month, no membership fee. Twelve months of tirzepatide on the annual plan total $1,548, equivalent to $129 a month. Twelve separate one-month plans at $199 would total $2,388, an $840 difference. The three- and six-month equivalents are $159 and $139 respectively. Confirm payment and renewal terms before choosing.

Costs $888 a year more than the cheapest option. The $79 semaglutide and $129 tirzepatide rates require 12-month plans. One-month plans are $139 and $199 respectively. Read the payment and refund terms before committing to a longer plan. Full numbers in our Coreage Rx tirzepatide review.

2. SuperHealthy Rx — $1,620 a year

$135 a month, no membership fee. Online provider review for compounded semaglutide and tirzepatide; provider visit and shipping included according to the offer.

Costs $120 a year more than the cheapest option. Confirm the total upfront payment, renewal, state availability and dispensing pharmacy. Full numbers in our SuperHealthy Rx tirzepatide review.

3. Likeness Rx — $2,388 a year

$199 a month, no membership fee. These are provider-published terms checked October 4, 2026. Prescription approval is conditional. Compounded medications are not FDA-approved; we have not tested the treatment, pharmacy fulfillment or patient outcomes.

Costs $888 a year more than the cheapest option. The lowest monthly equivalents accompany 12-month subscriptions: $948 for semaglutide or $1,548 for tirzepatide. One-month plans are $139 and $199. The page says the selected term renews automatically; check the amount due and cancellation date. Full numbers in our Likeness Rx tirzepatide review.

4. Trimi — $1,500 a year

$125 a month, no membership fee. $125 a month, flat at every dose, with no membership renewing behind it. Trimi also names its compounding pharmacies — VialsRx, with a Texas licence number, and GreenwichRx — which almost nobody else in this market does.

Nothing here is cheaper. Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months. Full numbers in our Trimi tirzepatide review.

5. Ozari Health — $1,500 a year

$125 a month, no membership fee. Ozari also advertises semaglutide at $86 a month — roughly $1,032 a year, the lowest annual figure in our whole table.

Nothing here is cheaper. Confirm whether $86 is a month-to-month rate or requires a longer commitment, and ask which pharmacy compounds it. Full numbers in our Ozari Health tirzepatide review.

6. Fifty 410 — $1,596 a year

$133 a month, no membership fee. Higher doses use the $549 block instead, or $183 a month. Over a year that is roughly $1,596 to $2,196 depending on which protocol you settle on.

Costs $96 a year more than the cheapest option. The $133 is the starter protocol. Moving to the high-dose protocol takes it to $183/month, and both are prepaid three-month commitments. Full numbers in our Fifty 410 tirzepatide review.

7. PlexusDx — $2,268 a year

$189 a month, no membership fee. PlexusDx names six 503A pharmacy partners and its prescribing physicians, with NPI numbers. The advertised "from $129" is a programme floor rather than the injection price, so budget from $189.

Costs $768 a year more than the cheapest option. The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier. Full numbers in our PlexusDx tirzepatide review.

8. Ivím Health — $2,388 a year

$199 a month, no membership fee. Most programmes in this band give you a portal and a shipping notification. Ivím reviews your dose weekly rather than monthly, which is a genuinely different product sold at a similar number.

Costs $888 a year more than the cheapest option. Pharmacy sourcing is not published. Ask which pharmacy fills your prescription and whether it is 503A or 503B before starting. Full numbers in our Ivím Health tirzepatide review.

Two programmes we leave out of this table

A price table only works if every row is a price for the same thing. Two are not, so we hold them out and say why: LifeMD — the monthly charge buys clinical care and insurance work, not medication — the drug is billed separately; Noom Med — medication is included, but at deliberately low doses well below those used in the trials; WeightWatchers Clinic — the monthly charge buys clinical care and insurance work, not medication — the drug is billed separately.

Both can be the right choice — LifeMD is excellent if your insurer will cover the medication, and Noom has the best coaching here. Neither belongs in a like-for-like price sort against a programme that includes the drug.

Six ways these prices hide

1. The renewing membership. A $39 introductory fee becomes $99 a month. Eden is the clearest example.
2. The fee quoted separately. Hims & Hers advertises $199 medication and bills $39 membership beside it.
3. The fee that buys no medication. Ro charges $149 a month for care only.
4. The cheapest tier that is a different product. "From $179" at Henry Meds is sublingual, not the weekly injection.
5. The price that climbs with your dose. Many programmes charge more as you titrate up to a useful dose.
6. The insured price quoted at cash payers. Those $25 a month figures require your plan to approve the prescription.

We walk through each of these with worked examples in how to cut your GLP-1 bill.

What tirzepatide is, briefly

A single weekly injection that activates two gut hormone receptors, GIP and GLP-1, rather than one.

In SURMOUNT-1, adults with obesity lost an average of 19.5% of body weight on 10 mg and 20.9% on 15 mg over 72 weeks.

SURMOUNT-5 compared the two drugs directly. Participants on tirzepatide lost an average of 50.3 lb (22.8 kg); those on semaglutide lost 33.1 lb (15.0 kg). If you are choosing between the two drugs on price, we compare them in tirzepatide vs semaglutide.

Common side effects: Nausea, diarrhoea, constipation and reflux, concentrated in the weeks after each dose increase.

Brand-name prices, for comparison

Through LillyDirect self-pay, single-dose Zepbound vials at 5 mg, 7.5 mg and 10 mg have been listed at $499/month, with lower starting doses nearer $299-$349.

Those are the FDA-approved products. Compounded versions are not reviewed by the FDA for safety, effectiveness or manufacturing quality — a real difference, and one worth understanding before choosing on price alone. See is compounded still legal.

How we ranked this

• True monthly cost (30%) — What you actually pay in month two — medication plus membership plus anything billed separately. Advertised teaser rates score nothing here.
• Price honesty (20%) — Whether the renewal price is visible before you hand over a card, and whether the number at checkout matches the number in the ad.
• Clinical support (20%) — Who prescribes, how you reach them between visits, and whether dose changes are reviewed by a person or applied on a schedule.
• Pharmacy sourcing (15%) — Whether the provider names its pharmacy, states the 503A/503B pathway, and offers FDA-approved options alongside compounded ones.
• Cancelling (15%) — How hard it is to stop. Prepaid multi-month plans that cannot be refunded are marked down here.

Coreage Rx pays us and holds the top slot in this table. Everything below it is in true cheapest-first order, the prices are exactly what we verified, and the programmes that undercut our featured pick are named in the section above rather than quietly dropped. Full terms on our disclosure page.