TrimRx vs Henry Meds

Both sell tirzepatide. TrimRx costs $399 a month and Henry Meds costs $449, a difference of $50 a month or about $600 a year. Over a year that is the whole question.

TrimRx is all-inclusive compounded pricing. Henry Meds is sublingual and oral formats. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though for a cash payer it usually is.

The yearly view. Over twelve months that gap is $600. On a treatment most people stay on for years rather than months, that compounds: five years at this difference is $3,000. That is the number worth deciding on, not the monthly one.

Side by side

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

Where the money actually goes

They differ on 1 of the 7 things we track, and behave the same on the other 6. The differences are what the price gap is actually buying.

What each one charges for: TrimRx

• Compounded tirzepatide advertised at $349/month.
• Checkout has been reported billing $399/month on ongoing month-to-month terms.
• Pricing is described as all-inclusive of consultation, medication and supplies.

Where it wins: One price covers consultation, medication and supplies. Watch for: Read the ongoing rate on the checkout screen, not the landing page. Reported billing is $399/month.

What each one charges for: Henry Meds

• Injectable tirzepatide listed at $399 for the first month and $449/month recurring.
• Oral tirzepatide tablets listed at $299 first month, $349/month recurring.
• Compounded semaglutide injection around $297/month; sublingual around $249/month with a $179/month tier.
• Three-month oral tirzepatide supply $1,047, or $891 paid in full.
• Three-month oral semaglutide supply $747, or $537 paid in full.
• Advertising states pricing "starts at $179/month", which corresponds to the lowest sublingual tier.

Where it wins: No membership fee layered on top of medication. Watch for: The advertised "starts at $179" is the sublingual tier. Weekly injectable tirzepatide renews at $449/month.

What each does well

TrimRx.

• One price covers consultation, medication and supplies.
• No separate membership fee.

Henry Meds.

• No membership fee layered on top of medication.
• Real choice of sublingual, oral tablet and injection.

How they score

Henry Meds scores higher overall at 3 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

Which saves you more

• Pick TrimRx if cost is the binding constraint. Over a year the gap is about $600, which is real money for the same class of medication.
• Pick Henry Meds if what it does better matters to you — no membership fee layered on top of medication.
• Ask both which pharmacy compounds the medication and whether it is a 503A or 503B facility. Neither publishes it.

The verdict

On the yearly arithmetic, TrimRx at $399 a month is the more defensible choice on arithmetic alone. Henry Meds earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: TrimRx and Henry Meds.

How they sit against everyone else