Trimi vs PlexusDx
$125/mo against $189/mo for tirzepatide. Which is worth it, and for whom.
Updated 2026-09-18 · every price checked by hand
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Both sell tirzepatide. Trimi costs $125 a month and PlexusDx costs $189, a difference of $64 a month or about $768 a year. Over a year that is the whole question.
Trimi is lowest flat price with named pharmacies. PlexusDx is pharmacy transparency and genetic testing. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though for a cash payer it usually is.
Side by side
| Trimi | PlexusDx | |
|---|---|---|
| Advertised from | $125 | $129 |
| Membership on top | None | None |
| True monthly cost | $125 | $189 |
| Roughly, per year | $1,500 | $2,268 |
| Price includes medication | Yes | Yes |
| Names its pharmacy | Yes | Yes |
| Our score | 4.6 / 5 | 4.4 / 5 |
Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.
Where Trimi wins
- The cheapest verified flat rate for compounded tirzepatide in this comparison.
- Names its pharmacies with a licence number and offers a certificate of analysis — almost nobody else in this market does.
- Price does not move as your dose is adjusted.
- No membership fee stacked on the medication price.
Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months.
Where PlexusDx wins
- The most detailed pharmacy disclosure in this comparison — six named 503A partners.
- Names its prescribing physicians along with their NPI numbers.
- No membership fee, and flat pricing across the dose range.
- Genetic and blood testing available alongside the prescription.
The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier.
How they score
| What we weigh | Weight | Trimi | PlexusDx |
|---|---|---|---|
| True monthly cost | 30% | 5 | 4.6 |
| Price honesty | 20% | 4.8 | 4.5 |
| Clinical support | 20% | 4 | 3.8 |
| Pharmacy sourcing | 15% | 4.8 | 4.9 |
| Cancelling | 15% | 4.2 | 4 |
Trimi scores higher overall at 4.6 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.
Which should you pick?
- Pick Trimi if cost is the binding constraint. Over a year the gap is about $768, which is real money for the same class of medication.
- Pick PlexusDx if what it does better matters to you — the most detailed pharmacy disclosure in this comparison — six named 503a partners.
- If sourcing matters, note that Trimi publishes which pharmacy compounds its medication and PlexusDx does not.
The verdict
On the yearly arithmetic, Trimi at $125 a month is the more defensible choice on arithmetic alone. PlexusDx earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: Trimi and PlexusDx.
How they sit against everyone else
| Programme | Per month | Per year | Extra vs cheapest |
|---|---|---|---|
| Coreage Rx Cheapest no membership fee | $199 | $2,388 | +$888 |
| Trimi no membership fee | $125 | $1,500 | — |
| Ozari Health no membership fee | $125 | $1,500 | — |
| Fifty 410 no membership fee | $133 | $1,596 | +$96 |
| PlexusDx no membership fee | $189 | $2,268 | +$768 |
| Ivím Health no membership fee | $199 | $2,388 | +$888 |
| Zealthy no membership fee | $216 | $2,592 | +$1,092 |
| Hims & Hers incl. $39 monthly fee | $238 | $2,856 | +$1,356 |
| Coby Health no membership fee | $239 | $2,868 | +$1,368 |
| Mochi Health incl. $79 monthly fee | $278 | $3,336 | +$1,836 |
| Eden incl. $99 monthly fee | $298 | $3,576 | +$2,076 |
| Lemonaid Health incl. $49 monthly fee | $348 | $4,176 | +$2,676 |