Trimi vs Fifty 410
$125/mo against $133/mo for tirzepatide. Which is worth it, and for whom.
Updated 2026-09-18 · every price checked by hand
Both sell tirzepatide. Trimi costs $125 a month and Fifty 410 costs $133, a difference of $8 a month or about $96 a year. Over a year that is the whole question.
Trimi is lowest flat price with named pharmacies. Fifty 410 is prepaid blocks with no subscription. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though for a cash payer it usually is.
The yearly view. Over twelve months that gap is $96. On a treatment most people stay on for years rather than months, that compounds: five years at this difference is $480. That is the number worth deciding on, not the monthly one.
Side by side
| Trimi | Fifty 410 | Difference | |
|---|---|---|---|
| Per month | $125 | $133 | $8 |
| Per year | $1,500 | $1,596 | $96 |
| Over five years | $7,500 | $7,980 | $480 |
| Membership included? | No fee | No fee |
Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.
Where the money actually goes
2 real differences between them. Everything else is identical, so the rest of the decision is money.
| Trimi | Fifty 410 | |
|---|---|---|
| Price is the same at every dose | Yes | No |
| Names the compounding pharmacy publicly | Yes | No |
What each one charges for: Trimi
- Price is the same at every prescribed dose.
- One flat charge covers medication, clinician visits, check-ins and free overnight shipping; no separate membership.
Where it wins: The cheapest verified flat rate for compounded tirzepatide in this comparison. Watch for: Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months.
What each one charges for: Fifty 410
- No membership, no subscription and no recurring charges — you buy a block outright.
- Provider consultation and free 1-2 day shipping included in the price.
Where it wins: Genuinely no subscription — you buy a block and nothing recurs. Watch for: The $133 is the starter protocol. Moving to the high-dose protocol takes it to $183/month, and both are prepaid three-month commitments.
What each does well
Trimi.
- The cheapest verified flat rate for compounded tirzepatide in this comparison.
- Names its pharmacies with a licence number and offers a certificate of analysis — almost nobody else in this market does.
Fifty 410.
- Genuinely no subscription — you buy a block and nothing recurs.
- Among the lowest tirzepatide rates verified.
Trimi scores higher overall at 4.6 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.
Which saves you more
On money alone: Trimi, by $96 a year. That is the entire calculation and we are not going to dress it up. The only reason to pay more is if Fifty 410 does something in the table above that you will actually use — and most people, most of the time, will not.
The verdict
On the yearly arithmetic, Trimi at $125 a month is the more defensible choice on arithmetic alone. Fifty 410 earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: Trimi and Fifty 410.
How they sit against everyone else
| Programme | Per month | Per year | Extra vs cheapest |
|---|---|---|---|
| Coreage Rx Cheapest no membership fee | $199 | $2,388 | +$888 |
| SuperHealthy Rx no membership fee | $135 | $1,620 | +$120 |
| Likeness Rx no membership fee | $199 | $2,388 | +$888 |
| Trimi no membership fee | $125 | $1,500 | — |
| Ozari Health no membership fee | $125 | $1,500 | — |
Read next
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