PlexusDx vs Henry Meds
$189/mo against $449/mo for tirzepatide. Which is worth it, and for whom.
Updated 2026-09-18 · every price checked by hand
How we make money: one company on this page — Coreage Rx — pays us a commission when a reader signs up through our link. It buys them nothing else: not a better score, not a higher place in the table, not the removal of a single criticism. Our scoring method and full disclosure are both public.
Both sell tirzepatide. PlexusDx costs $189 a month and Henry Meds costs $449, a difference of $260 a month or about $3,120 a year. Over a year that is the whole question.
PlexusDx is pharmacy transparency and genetic testing. Henry Meds is sublingual and oral formats. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though for a cash payer it usually is.
Side by side
| PlexusDx | Henry Meds | |
|---|---|---|
| Advertised from | $129 | $399 |
| Membership on top | None | None |
| True monthly cost | $189 | $449 |
| Roughly, per year | $2,268 | $5,388 |
| Price includes medication | Yes | Yes |
| Names its pharmacy | Yes | Not published |
| Our score | 4.4 / 5 | 3 / 5 |
Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.
Where PlexusDx wins
- The most detailed pharmacy disclosure in this comparison — six named 503A partners.
- Names its prescribing physicians along with their NPI numbers.
- No membership fee, and flat pricing across the dose range.
- Genetic and blood testing available alongside the prescription.
The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier.
Where Henry Meds wins
- No membership fee layered on top of medication.
- Real choice of sublingual, oral tablet and injection.
- Discounts for paying a multi-month block up front.
The advertised "starts at $179" is the sublingual tier. Weekly injectable tirzepatide renews at $449/month.
How they score
| What we weigh | Weight | PlexusDx | Henry Meds |
|---|---|---|---|
| True monthly cost | 30% | 4.6 | 2.3 |
| Price honesty | 20% | 4.5 | 2.8 |
| Clinical support | 20% | 3.8 | 3.7 |
| Pharmacy sourcing | 15% | 4.9 | 3.6 |
| Cancelling | 15% | 4 | 2.9 |
PlexusDx scores higher overall at 4.4 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.
Which should you pick?
- Pick PlexusDx if cost is the binding constraint. Over a year the gap is about $3,120, which is real money for the same class of medication.
- Pick Henry Meds if what it does better matters to you — no membership fee layered on top of medication.
- If sourcing matters, note that PlexusDx publishes which pharmacy compounds its medication and Henry Meds does not.
The verdict
On the yearly arithmetic, PlexusDx at $189 a month is the more defensible choice on arithmetic alone. Henry Meds earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: PlexusDx and Henry Meds.
How they sit against everyone else
| Programme | Per month | Per year | Extra vs cheapest |
|---|---|---|---|
| Coreage Rx Cheapest no membership fee | $199 | $2,388 | +$888 |
| Trimi no membership fee | $125 | $1,500 | — |
| Ozari Health no membership fee | $125 | $1,500 | — |
| Fifty 410 no membership fee | $133 | $1,596 | +$96 |
| PlexusDx no membership fee | $189 | $2,268 | +$768 |
| Ivím Health no membership fee | $199 | $2,388 | +$888 |
| Zealthy no membership fee | $216 | $2,592 | +$1,092 |
| Hims & Hers incl. $39 monthly fee | $238 | $2,856 | +$1,356 |
| Coby Health no membership fee | $239 | $2,868 | +$1,368 |
| Mochi Health incl. $79 monthly fee | $278 | $3,336 | +$1,836 |
| Eden incl. $99 monthly fee | $298 | $3,576 | +$2,076 |
| Lemonaid Health incl. $49 monthly fee | $348 | $4,176 | +$2,676 |