Guide

PlexusDx vs Eden

$189/mo against $298/mo for tirzepatide. Which is worth it, and for whom.

Illustration of two objects on a balance scale

Updated 2026-09-18 · every price checked by hand

How we make money: one company on this page — Coreage Rx — pays us a commission when a reader signs up through our link. It buys them nothing else: not a better score, not a higher place in the table, not the removal of a single criticism. Our scoring method and full disclosure are both public.


Both sell tirzepatide. PlexusDx costs $189 a month and Eden costs $298, a difference of $109 a month or about $1,308 a year. Over a year that is the whole question.

PlexusDx is pharmacy transparency and genetic testing. Eden is low advertised medication price. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though for a cash payer it usually is.

The yearly view. Over twelve months that gap is $1,308. On a treatment most people stay on for years rather than months, that compounds: five years at this difference is $6,540. That is the number worth deciding on, not the monthly one.

Side by side

PlexusDxEden
Advertised from$129$199
Membership on topNone$99/mo
True monthly cost$189$298
Roughly, per year$2,268$3,576
Price includes medicationYesYes
Names its pharmacyYesNot published
Our score4.4 / 53.1 / 5

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

Where the money actually goes

They differ on 2 of the 7 things we track, and behave the same on the other 5. The differences are what the price gap is actually buying.

PlexusDxEden
Names the compounding pharmacy publiclyYesNo
Offers an oral or sublingual optionYesNo

What each one charges for: PlexusDx

  • GLP-1 weight-loss programmes start at $129/month.
  • Compounded semaglutide injection listed at $189/month with no membership fee and the same price at every dose.
  • A $189/month microdose tier is offered for compounded semaglutide or tirzepatide.
  • No membership or platform fee is charged alongside the medication.
  • Publicly names six 503A pharmacy partners: Belmar, Strive, Epiq Scripts, Casa Pharma Rx, The Pharmacy Hub and Foothills.
  • Clinical oversight via LionMD, with named physicians and NPI numbers published.
  • Licensed providers in all 50 states; CLIA-certified labs for its testing line.

Where it wins: The most detailed pharmacy disclosure in this comparison — six named 503A partners. Watch for: The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier.

What each one charges for: Eden

  • Compounded semaglutide advertised at $99/month.
  • Compounded tirzepatide advertised at $199/month.
  • Membership is $39 as an introductory rate, then $99/month ongoing.
  • True ongoing cost for tirzepatide lands near $298/month once membership is included.

Where it wins: Genuinely low medication-only pricing. Watch for: The $99 semaglutide headline becomes roughly $198/month once the membership renews at its ongoing rate.

What each does well

PlexusDx.

  • The most detailed pharmacy disclosure in this comparison — six named 503A partners.
  • Names its prescribing physicians along with their NPI numbers.

Eden.

  • Genuinely low medication-only pricing.
  • Fast onboarding with flat rates across published dose ranges.

How they score

What we weighWeightPlexusDxEden
True monthly cost30%4.63.1
Price honesty20%4.52.6
Clinical support20%3.83.3
Pharmacy sourcing15%4.93.4
Cancelling15%43.1

PlexusDx scores higher overall at 4.4 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

Which saves you more

  • Pick PlexusDx if cost is the binding constraint. Over a year the gap is about $1,308, which is real money for the same class of medication.
  • Pick Eden if what it does better matters to you — genuinely low medication-only pricing.
  • If sourcing matters, note that PlexusDx publishes which pharmacy compounds its medication and Eden does not.

The verdict

On the yearly arithmetic, PlexusDx at $189 a month is the more defensible choice on arithmetic alone. Eden earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: PlexusDx and Eden.

How they sit against everyone else

ProgrammePer monthPer yearExtra vs cheapest
Coreage Rx Cheapest
no membership fee
$199$2,388+$888
Trimi
no membership fee
$125$1,500
Ozari Health
no membership fee
$125$1,500
Fifty 410
no membership fee
$133$1,596+$96
PlexusDx
no membership fee
$189$2,268+$768
Ivím Health
no membership fee
$199$2,388+$888
Zealthy
no membership fee
$216$2,592+$1,092
Hims & Hers
incl. $39 monthly fee
$238$2,856+$1,356
Coby Health
no membership fee
$239$2,868+$1,368
Mochi Health
incl. $79 monthly fee
$278$3,336+$1,836
Eden
incl. $99 monthly fee
$298$3,576+$2,076
Lemonaid Health
incl. $49 monthly fee
$348$4,176+$2,676

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