LifeMD vs Henry Meds
$149/mo against $449/mo for tirzepatide. Which is worth it, and for whom.
Updated 2026-09-18 · every price checked by hand
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Both sell tirzepatide. LifeMD costs $149 a month and Henry Meds costs $449, a difference of $300 a month or about $3,600 a year. Over a year that is the whole question.
LifeMD is insurance coordination. Henry Meds is sublingual and oral formats. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though for a cash payer it usually is.
The yearly view. Over twelve months that gap is $3,600. On a treatment most people stay on for years rather than months, that compounds: five years at this difference is $18,000. That is the number worth deciding on, not the monthly one.
Side by side
| LifeMD | Henry Meds | |
|---|---|---|
| Advertised from | $75 | $399 |
| Membership on top | None | None |
| True monthly cost | $149 | $449 |
| Roughly, per year | $1,788 | $5,388 |
| Price includes medication | No — billed separately | Yes |
| Names its pharmacy | N/A — FDA-approved product | Not published |
| Our score | 3.5 / 5 | 3 / 5 |
Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.
Where the money actually goes
They differ on 3 of the 7 things we track, and behave the same on the other 4. The differences are what the price gap is actually buying.
| LifeMD | Henry Meds | |
|---|---|---|
| Will pursue insurance coverage | Yes | No |
| Can dispense FDA-approved branded medication | Yes | No |
| Medication included in the monthly price | No | Yes |
What each one charges for: LifeMD
- GLP-1 injection programme listed at $75 first month, then $149/month.
- Annual plan advertised as low as $75/month.
- Programme fee does not include medication when medication is branded and billed to insurance.
- Markets insurance coordination that can reduce semaglutide cost to roughly $25/month where coverage applies.
Where it wins: Genuine clinician oversight with a physician-led model. Watch for: If your insurer declines, the $149/month programme fee still applies and the medication is extra.
What each one charges for: Henry Meds
- Injectable tirzepatide listed at $399 for the first month and $449/month recurring.
- Oral tirzepatide tablets listed at $299 first month, $349/month recurring.
- Compounded semaglutide injection around $297/month; sublingual around $249/month with a $179/month tier.
- Three-month oral tirzepatide supply $1,047, or $891 paid in full.
- Three-month oral semaglutide supply $747, or $537 paid in full.
- Advertising states pricing "starts at $179/month", which corresponds to the lowest sublingual tier.
Where it wins: No membership fee layered on top of medication. Watch for: The advertised "starts at $179" is the sublingual tier. Weekly injectable tirzepatide renews at $449/month.
What each does well
LifeMD.
- Genuine clinician oversight with a physician-led model.
- Insurance work is a core part of the service, not an afterthought.
Henry Meds.
- No membership fee layered on top of medication.
- Real choice of sublingual, oral tablet and injection.
How they score
| What we weigh | Weight | LifeMD | Henry Meds |
|---|---|---|---|
| True monthly cost | 30% | 3 | 2.3 |
| Price honesty | 20% | 3.3 | 2.8 |
| Clinical support | 20% | 4 | 3.7 |
| Pharmacy sourcing | 15% | 4.2 | 3.6 |
| Cancelling | 15% | 3.4 | 2.9 |
LifeMD scores higher overall at 3.5 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.
Which saves you more
- Pick LifeMD if cost is the binding constraint. Over a year the gap is about $3,600, which is real money for the same class of medication.
- Pick Henry Meds if what it does better matters to you — no membership fee layered on top of medication.
- Ask both which pharmacy compounds the medication and whether it is a 503A or 503B facility. Neither publishes it.
The verdict
On the yearly arithmetic, LifeMD at $149 a month is the more defensible choice on arithmetic alone. Henry Meds earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: LifeMD and Henry Meds.
How they sit against everyone else
| Programme | Per month | Per year | Extra vs cheapest |
|---|---|---|---|
| Coreage Rx Cheapest no membership fee | $199 | $2,388 | +$888 |
| Trimi no membership fee | $125 | $1,500 | — |
| Ozari Health no membership fee | $125 | $1,500 | — |
| Fifty 410 no membership fee | $133 | $1,596 | +$96 |
| PlexusDx no membership fee | $189 | $2,268 | +$768 |
| Ivím Health no membership fee | $199 | $2,388 | +$888 |
| Zealthy no membership fee | $216 | $2,592 | +$1,092 |
| Hims & Hers incl. $39 monthly fee | $238 | $2,856 | +$1,356 |
| Coby Health no membership fee | $239 | $2,868 | +$1,368 |
| Mochi Health incl. $79 monthly fee | $278 | $3,336 | +$1,836 |
| Eden incl. $99 monthly fee | $298 | $3,576 | +$2,076 |
| Lemonaid Health incl. $49 monthly fee | $348 | $4,176 | +$2,676 |