Guide

Fifty 410 vs Coby Health

$133/mo against $239/mo for tirzepatide. Which is worth it, and for whom.

Illustration of two objects on a balance scale

Updated 2026-09-18 · every price checked by hand


Both sell tirzepatide. Fifty 410 costs $133 a month and Coby Health costs $239, a difference of $106 a month or about $1,272 a year. Over a year that is the whole question.

Fifty 410 is prepaid blocks with no subscription. Coby Health is multi-month value with supplies included. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though for a cash payer it usually is.

The yearly view. Over twelve months that gap is $1,272. On a treatment most people stay on for years rather than months, that compounds: five years at this difference is $6,360. That is the number worth deciding on, not the monthly one.

Side by side

Fifty 410CobyDifference
Per month$133$239$106
Per year$1,596$2,868$1,272
Over five years$7,980$14,340$6,360
Membership included?No feeNo fee

Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.

Where the money actually goes

1 real differences between them. Everything else is identical, so the rest of the decision is money.

Fifty 410Coby
Month-to-month without prepaying a blockNoYes

What each one charges for: Fifty 410

  • No membership, no subscription and no recurring charges — you buy a block outright.
  • Provider consultation and free 1-2 day shipping included in the price.

Where it wins: Genuinely no subscription — you buy a block and nothing recurs. Watch for: The $133 is the starter protocol. Moving to the high-dose protocol takes it to $183/month, and both are prepaid three-month commitments.

What each one charges for: Coby Health

  • An at-home injection kit with alcohol pads and syringes is included.
  • Monthly plans can be cancelled at any time.

Where it wins: Injection supplies are included rather than something you source yourself. Watch for: The $179 figure is a multi-month rate. Month-to-month is $239.

What each does well

Fifty 410.

  • Genuinely no subscription — you buy a block and nothing recurs.
  • Among the lowest tirzepatide rates verified.

Coby Health.

  • Injection supplies are included rather than something you source yourself.
  • Monthly plan is genuinely cancel-anytime.

Fifty 410 scores higher overall at 4.2 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.

Which saves you more

On money alone: Fifty 410, by $1,272 a year. That is the entire calculation and we are not going to dress it up. The only reason to pay more is if Coby Health does something in the table above that you will actually use — and most people, most of the time, will not.

The verdict

On the yearly arithmetic, Fifty 410 at $133 a month is the more defensible choice on arithmetic alone. Coby Health earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: Fifty 410 and Coby Health.

How they sit against everyone else

ProgrammePer monthPer yearExtra vs cheapest
Coreage Rx Cheapest
no membership fee
$199$2,388+$888
SuperHealthy Rx
no membership fee
$135$1,620+$120
Likeness Rx
no membership fee
$199$2,388+$888
Trimi
no membership fee
$125$1,500—
Ozari Health
no membership fee
$125$1,500—

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Coreage Rx pays us a commission on sign-ups through our links. It does not affect our scores or rankings. How we rate · Disclosure