Coreage Rx vs Fifty 410
$199/mo against $133/mo for tirzepatide. Which is worth it, and for whom.
Updated 2026-09-18 · every price checked by hand
How we make money: one company on this page — Coreage Rx — pays us a commission when a reader signs up through our link. It buys them nothing else: not a better score, not a higher place in the table, not the removal of a single criticism. Our scoring method and full disclosure are both public.
Both sell tirzepatide. Fifty 410 costs $133 a month and Coreage Rx costs $199, a difference of $66 a month or about $792 a year. Over a year that is the whole question.
Coreage Rx is best overall on true monthly cost. Fifty 410 is prepaid blocks with no subscription. They are not aimed at the same person, and the cheaper one is not automatically the right answer — though for a cash payer it usually is.
Side by side
| Coreage Rx | Fifty 410 | |
|---|---|---|
| Advertised from | $149 | $133 |
| Membership on top | None | None |
| True monthly cost | $199 | $133 |
| Roughly, per year | $2,388 | $1,596 |
| Price includes medication | Yes | Yes |
| Names its pharmacy | Not published | Not published |
| Our score | 4.5 / 5 | 4.2 / 5 |
Prices verified 2026-09-18. "True monthly cost" is what you are billed in month two, once any introductory rate has lapsed and any membership has renewed.
Where Coreage Rx wins
- The advertised price is the billed price — no membership fee arrives in month two.
- Flat pricing across the dose range, so titrating up to 10 mg or 15 mg does not raise the bill.
- Lowest true monthly cost of any provider in this comparison once fees are included.
- Coaching and clinician access are included rather than sold separately.
The $99 and $149 rates are annual-plan prices. If you want month-to-month, budget $149 and $199 instead, and check the refund terms before prepaying a year.
Where Fifty 410 wins
- Genuinely no subscription — you buy a block and nothing recurs.
- Among the lowest tirzepatide rates verified.
- Unusually detailed public explanation of 503A standards and batch testing.
- No payment taken until a provider approves you.
The $133 is the starter protocol. Moving to the high-dose protocol takes it to $183/month, and both are prepaid three-month commitments.
How they score
| What we weigh | Weight | Coreage Rx | Fifty 410 |
|---|---|---|---|
| True monthly cost | 30% | 4.9 | 4.8 |
| Price honesty | 20% | 4.7 | 4.6 |
| Clinical support | 20% | 4.3 | 3.5 |
| Pharmacy sourcing | 15% | 4 | 4.2 |
| Cancelling | 15% | 4.4 | 3.3 |
Coreage Rx scores higher overall at 4.5 out of 5. The weights are published on how we rate, and so is the note about which of these is our paid featured partner.
Which should you pick?
- Pick Fifty 410 if cost is the binding constraint. Over a year the gap is about $792, which is real money for the same class of medication.
- Pick Coreage Rx if what it does better matters to you — the advertised price is the billed price — no membership fee arrives in month two.
- Ask both which pharmacy compounds the medication and whether it is a 503A or 503B facility. Neither publishes it.
The verdict
On the yearly arithmetic, Fifty 410 at $133 a month is the more defensible choice on arithmetic alone. Coreage Rx earns its premium only if you will actually use what it does differently. Read the full reviews before deciding: Coreage Rx and Fifty 410.
How they sit against everyone else
| Programme | Per month | Per year | Extra vs cheapest |
|---|---|---|---|
| Coreage Rx Cheapest no membership fee | $199 | $2,388 | +$888 |
| Trimi no membership fee | $125 | $1,500 | — |
| Ozari Health no membership fee | $125 | $1,500 | — |
| Fifty 410 no membership fee | $133 | $1,596 | +$96 |
| PlexusDx no membership fee | $189 | $2,268 | +$768 |
| Ivím Health no membership fee | $199 | $2,388 | +$888 |
| Zealthy no membership fee | $216 | $2,592 | +$1,092 |
| Hims & Hers incl. $39 monthly fee | $238 | $2,856 | +$1,356 |
| Coby Health no membership fee | $239 | $2,868 | +$1,368 |
| Mochi Health incl. $79 monthly fee | $278 | $3,336 | +$1,836 |
| Eden incl. $99 monthly fee | $298 | $3,576 | +$2,076 |
| Lemonaid Health incl. $49 monthly fee | $348 | $4,176 | +$2,676 |