Tirzepatide 15 mg: what it costs
Step 6 of the tirzepatide ladder, around weeks 21+. 6 providers charge the same here as at the starting dose — the rest may not.
Updated 2026-09-18 · every price checked by hand
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15 mg is step 6 of 6 on the tirzepatide ladder, reached around weeks 21+. The maximum approved dose, and the one that produced the largest average result in trials.
It is also the point where pricing starts to matter. On a programme that charges by dose, your bill climbs exactly as the treatment begins working. On a flat-rate programme, 15 mg costs what the starting dose cost — and over a full titration that difference is worth more than almost any advertised discount.
What 15 mg is for
15 mg produced the largest average result in SURMOUNT-1 — 20.9% over 72 weeks — and it is the top of the ladder. What gets lost in that figure is that it is an average of people who tolerated the maximum dose for eighteen months, which is not everybody. Reaching 15 mg is not a goal in itself, and stepping back down once you have reached your target is a normal thing to do rather than a retreat.
The evidence. In SURMOUNT-1, the 15 mg group lost an average of 20.9% of body weight over 72 weeks.
Not everybody needs to get here, and reaching it is not a measure of success. Many people do best settling lower.
Where 15 mg sits on the ladder
| Step | Dose | Roughly when |
|---|---|---|
| 1 | 2.5 mg | weeks 1-4 |
| 2 | 5 mg | weeks 5-8 |
| 3 | 7.5 mg | weeks 9-12 |
| 4 | 10 mg | weeks 13-16 |
| 5 | 12.5 mg | weeks 17-20 |
| 6 | 15 mg ← this page | weeks 21+ |
What 15 mg costs
6 of the providers we track hold a single price at every dose, so 15 mg costs the same as the starting dose. They are listed first below because at this rung that is the whole ballgame.
| Provider | Price at 15 mg | Per year | Score |
|---|---|---|---|
| Coreage Rx | $199 | $2,388 | 4.5 |
| Trimi | $125 | $1,500 | 4.6 |
| PlexusDx | $189 | $2,268 | 4.4 |
| Mochi Health | $278 | $3,336 | 3.6 |
| Eden | $298 | $3,576 | 3.1 |
| Remedy Meds | $399 | $4,788 | 3.5 |
Cheapest flat-rate option at 15 mg: Trimi at $125 a month, which is what it charges at every other rung too.
The remaining 12 providers either price by dose or do not publish a flat-rate commitment. Their quoted figures start at $125 a month, but that is the starting-dose price — ask specifically what 15 mg will cost before you assume it holds.
The question to ask before you start. "What will I be charged when I reach 15 mg?" If the answer is not the same number you were quoted at the start, you are on a tiered programme and should budget for the higher figure rather than the advertised one.
Do you need to go higher than 15 mg?
15 mg is the top of the ladder, so the question here is the opposite one: whether you need to stay this high. Some people step back down to a lower maintenance dose once they have reached their goal. That is a conversation for your prescriber.
Do I need to reach 15 mg to get results?
No. 10 mg produced 19.5% average loss against 20.9% at 15 mg — a real but modest difference. Plenty of people do best settling lower and staying there, which beats reaching the maximum and stopping.
Compounded preparations are not FDA-approved, and approved oral GLP-1s now start around $149 — see the approved pills. Dosing belongs to your prescriber, not this page.