Zepbound alternatives
Zepbound is tirzepatide. Here is what else delivers the same molecule, what it costs, and what you give up.
Updated 2026-09-18 · every price checked by hand
How we make money: one company on this page — Coreage Rx — pays us a commission when a reader signs up through our link. It buys them nothing else: not a better score, not a higher place in the table, not the removal of a single criticism. Our scoring method and full disclosure are both public.
Zepbound is Eli Lilly’s brand of tirzepatide, approved for weight management. Self-pay pricing has been listed around $299 to $499 a month, which is what sends most people looking for alternatives.
The realistic alternatives fall into two groups: compounded tirzepatide, which is the same molecule prepared by a pharmacy and not FDA-approved, and a different drug entirely such as semaglutide or one of the new approved pills. This page covers the first group, priced honestly.
What gets a programme onto this table
- Delivers tirzepatide — the same active ingredient as Zepbound.
- Monthly price includes the medication.
- Sorted cheapest first on the billed figure.
18 of the 21 providers we track qualify. Every figure checked by hand and verified 2026-09-18 and re-checked periodically.
The list
Every row below is priced against Zepbound at $499 a month, and sorted by how much it saves you over a year. We use the $499 self-pay figure listed for the 5 mg, 7.5 mg and 10 mg single-dose vials; lower starting doses have been listed nearer $299. Ranked on our overall score rather than price alone — the cheapest option is on the cheapest tirzepatide page.
| # | Provider | Per month | Saves vs Zepbound | Per year |
|---|---|---|---|---|
| 1 | Coreage Rx | $199 | $3,600/yr | $2,388 |
| 2 | Trimi | $125 | $4,488/yr | $1,500 |
| 3 | PlexusDx | $189 | $3,720/yr | $2,268 |
| 4 | Ozari Health | $125 | $4,488/yr | $1,500 |
| 5 | Fifty 410 | $133 | $4,392/yr | $1,596 |
| 6 | Ivím Health | $199 | $3,600/yr | $2,388 |
| 7 | Mochi Health | $278 | $2,652/yr | $3,336 |
| 8 | Coby Health | $239 | $3,120/yr | $2,868 |
| 9 | Hims & Hers | $238 | $3,132/yr | $2,856 |
| 10 | Ro | $448 | $612/yr | $5,376 |
| 11 | Zealthy | $216 | $3,396/yr | $2,592 |
| 12 | Remedy Meds | $399 | $1,200/yr | $4,788 |
| 13 | Lemonaid Health | $348 | $1,812/yr | $4,176 |
| 14 | Eden | $298 | $2,412/yr | $3,576 |
| 15 | Henry Meds | $449 | $600/yr | $5,388 |
| 16 | TrimRx | $399 | $1,200/yr | $4,788 |
| 17 | Willow | $399 | $1,200/yr | $4,788 |
| 18 | MEDVi | $399 | $1,200/yr | $4,788 |
Cheapest qualifying option: Trimi at $125 a month. Our featured partner is pinned to the top of the list where it qualifies — see how we rate for who scores higher.
1. Coreage Rx — Best overall on true monthly cost
$199 a month, no membership fee. Flat-rate telehealth program for compounded GLP-1s. The medication, the clinician visits and the ongoing check-ins are quoted as one number, with no separate membership billed alongside it.
The $99 and $149 rates are annual-plan prices. If you want month-to-month, budget $149 and $199 instead, and check the refund terms before prepaying a year. Read the full Coreage Rx review.
2. Trimi — Lowest flat price with named pharmacies
$125 a month, no membership fee. Flat-rate compounded GLP-1 programme on annual plans, with medical oversight through the Arora Health clinician network and publicly named 503A compounding pharmacies.
Both headline prices are annual-plan rates. Confirm the month-to-month figure and the refund terms before prepaying twelve months. Read the full Trimi review.
3. PlexusDx — Pharmacy transparency and genetic testing
$189 a month, no membership fee. Prescription GLP-1 and peptide programmes with no membership fee, built around genetic testing, using independent clinicians and a publicly listed set of 503A pharmacies.
The advertised "from $129" is the programme floor. Budget $189/month for the compounded injection tier. Read the full PlexusDx review.
4. Ozari Health — Lowest advertised semaglutide price
$125 a month, no membership fee. Flat-rate compounded GLP-1 telehealth service operating in all 50 states, with physician review through the Arora Health network and a dedicated health concierge.
Confirm whether $86 is a month-to-month rate or requires a longer commitment, and ask which pharmacy compounds it. Read the full Ozari Health review.
Questions we get asked
Is compounded tirzepatide the same as Zepbound?
Same active ingredient, different product. Zepbound is manufactured and FDA-approved; compounded tirzepatide is prepared by a pharmacy against a prescription and has not been reviewed by the FDA for safety, effectiveness or manufacturing quality.
Is there a cheaper way to get Zepbound itself?
Possibly. Manufacturer self-pay channels have brought the price down considerably, and from July 2026 eligible Medicare beneficiaries may access certain GLP-1s for $50 a month.
Two things worth knowing before you buy on price
Compounded preparations are not FDA-approved. Two approved oral GLP-1s now start around $149 a month, and from 1 July 2026 eligible Medicare beneficiaries can access certain GLP-1s for $50 a month — both of which beat a large part of this market. See the approved pills and the Medicare programme.
In SURMOUNT-1, adults with obesity lost an average of 19.5% of body weight on 10 mg and 20.9% on 15 mg over 72 weeks. That figure comes from a controlled trial of the active ingredient, not from any particular seller's product.